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FANCG Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-2566

Novus Biologicals, part of Bio-Techne
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NB100-2566
NB100-2566SS

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunoblotting, Western Blot

Cited:

Block/Neutralize, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Product Specifications

Immunogen

A peptide corresponding to the C-terminus of human FANCG (within amino acids 550-622). [SwissProt# O15287]

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: mouse (88%).

Localization

The major form is nuclear. The minor form is cytoplasmic.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

69 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for FANCG Antibody

Western Blot: FANCG Antibody [NB100-2566]

Western Blot: FANCG Antibody [NB100-2566]

Western Blot: FANCG Antibody [NB100-2566] - Detection of FANC G in transfected COS1 cell lysate.

Applications for FANCG Antibody

Application
Recommended Usage

Immunoblotting

reported in scientific literature (PMID 24910428)

Western Blot

1:1000
Application Notes
In Western Blot, a band is seen at approximately 69 kDa. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Whole antisera

Preservative

No Preservative

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: FANCG

FANCG, involved in Fanconi anemia, confers resistance to both hygromycin and mitomycin C. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies. A minimum of 8 FA genes have been identified.

Long Name

Fanconi Anemia Complementation Group G

Alternate Names

XRCC9

Entrez Gene IDs

2189 (Human)

Gene Symbol

FANCG

UniProt

Additional FANCG Products

Product Documents for FANCG Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for FANCG Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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