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FANCL Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00055120-B01P

Novus Biologicals, part of Bio-Techne
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H00055120-B01P

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

FANCL (AAH54517, 1 a.a. - 375 a.a.) full-length human protein. MAVTEASLLRQCPLLLPQNRSKTVYEGFISAQGRDFHLRIVLPEDLQLKNARLLCSWQLRTILSGYHRIVQQRMQHSPDLMSFMMELKMLLEVALKNRQELYALPPPPQFYSSLIEEIGTLGWDKLVYADTCFSTIKLKAEDASGREHLITLKLKAKYPAESPDYFVDFPVPFCASWTPQSSLISIYSQFLAAIESLKAFWDVMDEIDEKTWVLEPEKPPRSATARRIALGNNVSINIEVDPRHPTMLPECFFLGADRVVKPLGIKLSRNIHLWDPENSVLQNLKDVLEIDFPARAILEKSDFTMDCGICYAYQLDGTIPDQVCDNSQCGQPFHQICLYEWLRGLLTSRQSFNVIFGECPYCSKPITLKMSGRKH

Specificity

FANCL - Fanconi anemia, complementation group L,

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Scientific Data Images for FANCL Antibody

Western Blot: FANCL Antibody [H00055120-B01P]

Western Blot: FANCL Antibody [H00055120-B01P]

Western Blot: FANCL Antibody [H00055120-B01P] - Analysis of FANCL expression in transfected 293T cell line by FANCL polyclonal antibody. Lane 1: FANCL transfected lysate(41.36 KDa). Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: FANCL Antibody [H00055120-B01P]

Immunocytochemistry/ Immunofluorescence: FANCL Antibody [H00055120-B01P]

Immunocytochemistry/Immunofluorescence: FANCL Antibody [H00055120-B01P] - Analysis of purified antibody to FANCL on HeLa cell. (antibody concentration 10 ug/ml)

Applications for FANCL Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:10-1:500

Western Blot

1:500
Application Notes
Antibody reactive against transfected lysate for western blot. It has also been used for ELISA and immunofluorescence.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: FANCL

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]

Alternate Names

E3 ubiquitin-protein ligase FANCL, EC 6.3.2.-, FAAP43PHF9FLJ10335, Fanconi anemia group L protein, Fanconi anemia, complementation group L, Fanconi anemia-associated polypeptide of 43 kDa, PHD finger protein 9, POG

Entrez Gene IDs

55120 (Human)

Gene Symbol

FANCL

Additional FANCL Products

Product Documents for FANCL Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for FANCL Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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