FANCL Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84758

Novus Biologicals, part of Bio-Techne
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NBP1-84758
NBP1-84758-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all FANCL Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: ALKNRQELYALPPPPQFYSSLIEEIGTLGWDKLVYADTCFSTIKLKAEDASGREHLITLKLKAKYPAESPDYFVDFPVPFC

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FANCL Antibody

Western Blot: FANCL Antibody [NBP1-84758]

Western Blot: FANCL Antibody [NBP1-84758]

Western Blot: FANCL Antibody [NBP1-84758] - Analysis in human cell line NTERA-2.
Immunocytochemistry/ Immunofluorescence: FANCL Antibody [NBP1-84758]

Immunocytochemistry/ Immunofluorescence: FANCL Antibody [NBP1-84758]

Immunocytochemistry/Immunofluorescence: FANCL Antibody [NBP1-84758] - Staining of human cell line U-2 OS shows localization to nuclear bodies & vesicles. Antibody staining is shown in green.
FANCL Antibody

Immunohistochemistry-Paraffin: FANCL Antibody [NBP1-84758] -

Immunohistochemistry-Paraffin: FANCL Antibody [NBP1-84758] -Staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.
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Applications for FANCL Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FANCL

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]

Alternate Names

E3 ubiquitin-protein ligase FANCL, EC 6.3.2.-, FAAP43PHF9FLJ10335, Fanconi anemia group L protein, Fanconi anemia, complementation group L, Fanconi anemia-associated polypeptide of 43 kDa, PHD finger protein 9, POG

Gene Symbol

FANCL

Additional FANCL Products

Product Documents for FANCL Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for FANCL Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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