FBXL20 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-47458

Novus Biologicals, part of Bio-Techne
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NBP2-47458
NBP2-47458-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all FBXL20 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: MRRDVNGVTKSRFEMFSNSDEAVINK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FBXL20 Antibody

Western Blot: FBXL20 Antibody [NBP2-47458]

Western Blot: FBXL20 Antibody [NBP2-47458]

Western Blot: FBXL20 Antibody [NBP2-47458] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue.
Immunohistochemistry: FBXL20 Antibody [NBP2-47458]

Immunohistochemistry: FBXL20 Antibody [NBP2-47458]

Immunohistochemistry: FBXL20 Antibody [NBP2-47458] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts and Leydig cells.

Applications for FBXL20 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FBXL20

FBXL20 (F-Box And Leucine-Rich Repeat Protein 20) belongs to the F-box protein family which are involved in ubiquitination. Specifically, FBXL20 has an important role in neural transmission and regulating proteasome-mediated degradation of RIM1. FBXL20 is known to have interactions with CUL1, RIMS1, SKP1, RAD23B and COL7A1. FBXL20 has been studied in relation to anuria, renal vascular disease, nephropathy, breast cancer and urinary tract obstruction.

Alternate Names

DKFZp564O2364, Fbl2, Fbl20, F-box and leucine-rich repeat protein 20FLJ21037, F-box protein FBL2, F-box/LRR-repeat protein 20, F-box/LRR-repeat protein 2-like, MGC15482

Gene Symbol

FBXL20

Additional FBXL20 Products

Product Documents for FBXL20 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FBXL20 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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