FBXW7/Cdc4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-30920

Novus Biologicals, part of Bio-Techne
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NBP3-30920-100ug
NBP3-30920-25ug
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all FBXW7/Cdc4 Antibodies »

Product Specifications

Immunogen

Synthetic peptide dervied from the human FBXW7/Cdc4 protein

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for FBXW7/Cdc4 Antibody

FBXW7/Cdc4 Antibody

Western Blot: FBXW7/Cdc4 Antibody [NBP3-30920] -

Western Blot: FBXW7/Cdc4 Antibody [NBP3-30920] - Western blot using FBXW7/Cdc4 antibody (Cat. No. NBP3-30920) on human brain lysate (15 ug/lane). Antibody used at 10 ug/ml (1) and 1 ug/ml (2). Secondary antibody, mouse anti-rabbit HRP used at 1:50k dilution.

Applications for FBXW7/Cdc4 Antibody

Application
Recommended Usage

Western Blot

: 1-5 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Ammonium sulfate precipitation

Formulation

Phosphate buffered saline

Preservative

0.08% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: FBXW7/Cdc4

Auxin-inducible degron (AID) technology allows rapid depletion of proteins in animal cells and fungi. Auxin includes chemicals such as IAA (indole-3-aceticacid) and NAA (1-naphtalene acetic acid) and includes inhibitors in plants. For the degradation, and SCF ubiquitin ligase complex containing the TIR1 protein is activated via the association of auxin with TIR1. Because the core SCF components are conserved in all eukaryotic cells, it is possible to transplant the degradation pathway to yeast and mammalian cells by expressing TIR1. In those cells expressing TIR1, a protein fused with degron (AID degron) derived from AUX/IAA can be rapidly degraded in the presence of auxin. Anti-mini-AID tag can detected both mini-AID-tag and full-length AID-tag.

Long Name

F-box and WD Repeat Domain Containing 7

Alternate Names

AGO, Archipelago Homolog, Cdc4, FBW6, Fbw7, FBX30, FBXO30, FBXW6, SCF(Fbw7), SEL10

Gene Symbol

FBXW7

Additional FBXW7/Cdc4 Products

Product Documents for FBXW7/Cdc4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for FBXW7/Cdc4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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