Fc gamma RII/CD32 Antibody (3D3) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-09138

Novus Biologicals, part of Bio-Techne
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NBP3-09138
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Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 3D3

Format

BSA Free

Concentration

1 mg/ml

View all Fc gamma RII/CD32 Antibodies »

Product Specifications

Immunogen

Purified glycosylated recombinant human FcgammaRIIa2

Specificity

The mouse monoclonal antibody 3D3 recognizes an extracellular epitope of CD32, a 40 kDa polymorphic transmembrane glycoprotein serving as the low affinity receptor for aggregated IgG. This antibody recognizes CD32 isoforms on B cells of all donors, but on platelets, monocytes, and granulocytes of only some donors (131R variant, but not 131H variant).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for Fc gamma RII/CD32 Antibody (3D3) - BSA Free

Flow Cytometry: Fc gamma RII/CD32 Antibody (3D3) - BSA Free [NBP3-09138] -

Mass cytometry (surface staining) of human peripheral blood with anti-CD32 (3D3) 167Er. Gated on singlets.

Applications for Fc gamma RII/CD32 Antibody (3D3) - BSA Free

Application
Recommended Usage

Flow Cytometry

2-6 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Fc gamma RII/CD32

CD32 is a receptor for the Fc region of complexed or aggregated immunoglobulins gamma. This is a low affinity receptor. It is Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in downmodulation of previous state of cell activation triggered via antigen receptors on B cells (BCR), T cells (TCR) or via another Fc receptor.

Long Name

Fc gamma Receptor II

Alternate Names

FcgRII

Gene Symbol

FCGR2B

Additional Fc gamma RII/CD32 Products

Product Documents for Fc gamma RII/CD32 Antibody (3D3) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Fc gamma RII/CD32 Antibody (3D3) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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