Fc gamma RIIIB/CD16b Antibody (24)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-12795

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 24

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Fc gamma RIIIB/CD16b Antibodies »

Product Specifications

Immunogen

This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Fc gamma RIIIB/CD16b (Uniprot#: O75015.2; Met1-Ser200).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

This antibody can be stored at 2-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Fc gamma RIIIB/CD16b Antibody (24)

Immunohistochemistry-Paraffin: Fc gamma RIIIB/CD16b Antibody (24) [NBP3-12795]

Immunohistochemistry-Paraffin: Fc gamma RIIIB/CD16b Antibody (24) [NBP3-12795]

Immunohistochemistry-Paraffin: Fc gamma RIIIB/CD16b Antibody (24) [NBP3-12795] - Staining of human CD16b in human spleen with mouse monoclonal antibody at 1:2000 dilution.
Immunohistochemistry-Paraffin: Fc gamma RIIIB/CD16b Antibody (24) [NBP3-12795]

Immunohistochemistry-Paraffin: Fc gamma RIIIB/CD16b Antibody (24) [NBP3-12795]

Immunohistochemistry-Paraffin: Fc gamma RIIIB/CD16b Antibody (24) [NBP3-12795] - Staining of human CD16b in human liver with mouse monoclonal antibody at 1:2000 dilution.

Applications for Fc gamma RIIIB/CD16b Antibody (24)

Application
Recommended Usage

Immunohistochemistry

1:500-1:3000

Immunohistochemistry-Paraffin

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Fc gamma RIIIB/CD16b

CD16 (FcgRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgRIII is expressed in two forms FcgRIII-A and -B. FcgRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FceRI-g subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgRIII-A is associated, moreover, with FceRI-b subunit. Besides IgG, FceRI-A can be triggered also by oligomeric IgE. FcgRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.

Long Name

Fc gamma Receptor III

Alternate Names

CD16b, FCG3, FCGR3B, FcgRIIIB, FcR-10, FCRIIIB, IGFR3

Gene Symbol

FCGR3B

Additional Fc gamma RIIIB/CD16b Products

Product Documents for Fc gamma RIIIB/CD16b Antibody (24)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Fc gamma RIIIB/CD16b Antibody (24)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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