FCRN/FCGRT Antibody (FCGRT/2932)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-07228

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin, Protein Array

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # FCGRT/2932

Concentration

0.2 mg/ml

View all FCRN Antibodies »

Product Specifications

Immunogen

Recombinant fragment of human FCRN/FCGRT protein (around aa 24-215) (Exact sequence is proprietary) (Uniprot: P55899)

Localization

Cell Surface and Cytoplasmic

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Theoretical MW

46 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-08224)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for FCRN/FCGRT Antibody (FCGRT/2932)

Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody (FCGRT/2932) [NBP3-07228]

Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody (FCGRT/2932) [NBP3-07228]

Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody (FCGRT/2932) [NBP3-07228] - Formalin-fixed, paraffin-embedded human Testicular Cancer stained with FCRN/FCGRT Mouse Monoclonal Antibody (FCRN/FCGRT/2932).
Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody (FCGRT/2932) [NBP3-07228]

Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody (FCGRT/2932) [NBP3-07228]

Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody (FCGRT/2932) [NBP3-07228] - Formalin-fixed, paraffin-embedded human Cerebellum stained with FCRN/FCGRT Mouse Monoclonal Antibody (FCRN/FCGRT/2932).
Protein Array: FCRN/FCGRT Antibody (FCGRT/2932) [NBP3-07228]

Protein Array: FCRN/FCGRT Antibody (FCGRT/2932) [NBP3-07228]

Protein Array: FCRN/FCGRT Antibody (FCGRT/2932) [NBP3-07228] - Analysis of Protein Array containing >19,000 full-length human proteins using FCRN/FCGRT Mouse Monoclonal Antibody (FCRN/FCGRT/2932).

Applications for FCRN/FCGRT Antibody (FCGRT/2932)

Application
Recommended Usage

Immunohistochemistry-Paraffin

2-4 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 2-4ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: FCRN

The FCGRT gene encodes a 365 amino acid long, 39 kDA IgG receptor FcRn large subunit p51 protein that transfers immunoglobulin G antibodies across the placenta from mother to fetus, as well as functions to protect the antibody from degradation. FCGRT interacts with genes CA6, ELANE, AZGP1, B2M, and ALB. It has been linked to diseases such as: lupus, nephritis, leukemia, arthritis, immunodeficiency, epidermolysis bullosa acquisita, persistent fetal circulation syndrome, and pemphigus.

Long Name

Neonatal Fc Receptor

Alternate Names

FCGRT

Gene Symbol

FCGRT

UniProt

P55899

Additional FCRN Products

Product Documents for FCRN/FCGRT Antibody (FCGRT/2932)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for FCRN/FCGRT Antibody (FCGRT/2932)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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