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FCRN/FCGRT Antibody (FCGRT/2932) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-08224

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin, Protein Array

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # FCGRT/2932

Format

Azide and BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

Recombinant fragment of human FCRN/FCGRT protein (around aa 24-215) (Exact sequence is proprietary) (Uniprot: P55899)

Localization

Cell Surface and Cytoplasmic

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Theoretical MW

46 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

1.0 mg/ml of antibody purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS WITHOUT BSA & azide. Also available at 200 ug/ml WITH BSA & azide (NBP3-07228).

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for FCRN/FCGRT Antibody (FCGRT/2932) - Azide and BSA Free

Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody (FCGRT/2932) - Azide and BSA Free [NBP3-08224]

Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody (FCGRT/2932) - Azide and BSA Free [NBP3-08224]

Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody (FCGRT/2932) - Azide and BSA Free [NBP3-08224] - Formalin-fixed, paraffin-embedded human Cerebellum stained with FCRN/FCGRT Mouse Monoclonal Antibody (FCRN/FCGRT/2932).
Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody (FCGRT/2932) - Azide and BSA Free [NBP3-08224]

Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody (FCGRT/2932) - Azide and BSA Free [NBP3-08224]

Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody (FCGRT/2932) - Azide and BSA Free [NBP3-08224] - Formalin-fixed, paraffin-embedded human Testicular Cancer stained with FCRN/FCGRT Mouse Monoclonal Antibody (FCRN/FCGRT/2932).
Protein Array: FCRN/FCGRT Antibody (FCGRT/2932) - Azide and BSA Free [NBP3-08224]

Protein Array: FCRN/FCGRT Antibody (FCGRT/2932) - Azide and BSA Free [NBP3-08224]

Protein Array: FCRN/FCGRT Antibody (FCGRT/2932) - Azide and BSA Free [NBP3-08224] - Analysis of Protein Array containing >19,000 full-length human proteins using FCRN/FCGRT Mouse Monoclonal Antibody (FCRN/FCGRT/2932).

Applications for FCRN/FCGRT Antibody (FCGRT/2932) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

2-4 ug/ml
Application Notes
Immunohistochemistry Formalin-fixed: 2-4ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

Background: FCRN

The FCGRT gene encodes a 365 amino acid long, 39 kDA IgG receptor FcRn large subunit p51 protein that transfers immunoglobulin G antibodies across the placenta from mother to fetus, as well as functions to protect the antibody from degradation. FCGRT interacts with genes CA6, ELANE, AZGP1, B2M, and ALB. It has been linked to diseases such as: lupus, nephritis, leukemia, arthritis, immunodeficiency, epidermolysis bullosa acquisita, persistent fetal circulation syndrome, and pemphigus.

Long Name

Neonatal Fc Receptor

Alternate Names

FCGRT

Gene Symbol

FCGRT

Additional FCRN Products

Product Documents for FCRN/FCGRT Antibody (FCGRT/2932) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for FCRN/FCGRT Antibody (FCGRT/2932) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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