FGF-23 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-55423

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunoprecipitation, Peptide ELISA, Western Blot

Cited:

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all FGF-23 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-RHTRSAEDDSERD corresponding to internal region according to NP_065689.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Theoretical MW

28 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for FGF-23 Antibody

Western Blot: FGF-23 Antibody [NB100-55423]

Western Blot: FGF-23 Antibody [NB100-55423]

Western Blot: FGF-23 Antibody [NB100-55423] - Staining of Human Brain (Hippocampus) lysate (35ug protein in RIPA buffer). Detected by chemiluminescence.

Applications for FGF-23 Antibody

Application
Recommended Usage

Immunoprecipitation

1:10 - 1:500

Peptide ELISA

Detection limit 1:8000

Western Blot

0.3 - 10 ug/ml
Application Notes
WB: Approx. 28+37 kDa band bands observed in human brain is reported in scientific literature (PMID: 18682534). IP reactivity reported in (PMID: 22393163).
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: FGF-23

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The product of this gene inhibits renal tubular phosphate transport. This gene was identified by its mutations associated with autosomal dominant hypophosphatemic rickets (ADHR), an inherited phosphate wasting disorder. Abnormally high level expression of this gene was found in oncogenic hypophosphatemic osteomalacia (OHO), a phenotypically similar disease caused by abnormal phosphate metabolism. Mutations in this gene have also been shown to cause familial tumoral calcinosis with hyperphosphatemia.

Long Name

Fibroblast Growth Factor 23

Alternate Names

FGF23

Entrez Gene IDs

8074 (Human)

Gene Symbol

FGF23

UniProt

Q9GZV9

Additional FGF-23 Products

Product Documents for FGF-23 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for FGF-23 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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