FGFR1 Antibody (3D4F7) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-47451

Novus Biologicals, part of Bio-Techne
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NBP1-47451
NBP1-47451-0.025ml
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Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 3D4F7

Format

BSA Free

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all FGFR1 Antibodies »

Product Summary for FGFR1 Antibody (3D4F7) - BSA Free

Immunogen

Purified recombinant extracellular fragment of human FGFR1 (aa22-376) fused with hIgGFc tag expressed in HEK293 cells.

Reactivity Notes

Human

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Theoretical MW

92 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for FGFR1 Antibody (3D4F7) - BSA Free

Western Blot: FGFR1 Antibody (3D4F7)BSA Free [NBP1-47451]

Western Blot: FGFR1 Antibody (3D4F7)BSA Free [NBP1-47451]

Western Blot: FGFR1 Antibody (3D4F7) [NBP1-47451] - Analysis using anti-FGFR1 monoclonal antibody against extracellular domain of human FGFR1 (aa33-376).

Applications for FGFR1 Antibody (3D4F7) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Western Blot

1: 500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Ascites

Format

BSA Free

Preservative

0.03% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FGFR1

The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Long Name

Fibroblast Growth Factor Receptor 1

Alternate Names

CD331, FGF R1, Flt-2

Gene Symbol

FGFR1

Additional FGFR1 Products

Product Documents for FGFR1 Antibody (3D4F7) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for FGFR1 Antibody (3D4F7) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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