FGFR3 [p Tyr724] Antibody (SR2305)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21595

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21595-100ul
NBP3-21595-50ul
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Human, Mouse

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2305

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all FGFR3 Antibodies »

Product Summary for FGFR3 [p Tyr724] Antibody (SR2305)

Immunogen

A synthesized peptide derived from human phospho-FGFR3 [Tyr724] (Uniprot #: P22607)

Modification

p Tyr724

Specificity

Detects endogenous levels of total phospho-FGFR3 [Tyr724]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

96 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for FGFR3 [p Tyr724] Antibody (SR2305)

Western Blot: FGFR3 [p Tyr 724] Antibody (SR2305) [NBP3-21595] -

Western Blot: FGFR3 [p Tyr 724] Antibody (SR2305) [NBP3-21595] - Western blot analysis using NBP3-21595 in (1) MCF7 treated with pervanadate cell lysate; (2) untreated.

Applications for FGFR3 [p Tyr724] Antibody (SR2305)

Application
Recommended Usage

Flow Cytometry

1:50

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunoprecipitation

1:50

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FGFR3

FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGF R1 through 5. FGF Rs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGF R1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGF R5 does not. Multiple forms of FGF R1, 2, and 3 are generated by alternative splicing

Long Name

Fibroblast Growth Factor Receptor 3

Alternate Names

CD333, CEK, FGF R3, JTK4

Gene Symbol

FGFR3

Additional FGFR3 Products

Product Documents for FGFR3 [p Tyr724] Antibody (SR2305)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FGFR3 [p Tyr724] Antibody (SR2305)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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