FGFR4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84585

Novus Biologicals, part of Bio-Techne
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NBP1-84585
NBP1-84585-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all FGFR4 Antibodies »

Product Summary for FGFR4 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: EEVELEPCLAPSLEQQEQELTVALGQPVRLCCGRAERGGHWYKEGSRLAPAGRVRGWRGRLEIASFLP

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (87%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FGFR4 Antibody

Immunohistochemistry-Paraffin: FGFR4 Antibody [NBP1-84585]

Immunohistochemistry-Paraffin: FGFR4 Antibody [NBP1-84585]

Immunohistochemistry-Paraffin: FGFR4 Antibody [NBP1-84585] - Staining of human liver shows moderate cytoplasmic positivity in hepatocytes.
Immunohistochemistry-Paraffin: FGFR4 Antibody [NBP1-84585]

Immunohistochemistry-Paraffin: FGFR4 Antibody [NBP1-84585]

Immunohistochemistry-Paraffin: FGFR4 Antibody [NBP1-84585] - Staining of human gall bladder shows strong cytoplasmic and membrane positivity in glandular cells.
Immunohistochemistry-Paraffin: FGFR4 Antibody [NBP1-84585]

Immunohistochemistry-Paraffin: FGFR4 Antibody [NBP1-84585]

Immunohistochemistry-Paraffin: FGFR4 Antibody [NBP1-84585] - Staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.

Applications for FGFR4 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50-1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FGFR4

FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGF R1 through 5. FGF Rs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGF R1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGF R5 does not. Multiple forms of FGF R1, 2, and 3 are generated by alternative splicing

Long Name

Fibroblast Growth Factor Receptor 4

Alternate Names

CD334, FGF R4

Gene Symbol

FGFR4

Additional FGFR4 Products

Product Documents for FGFR4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FGFR4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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