Fgr Antibody (1B12)

Novus Biologicals, part of Bio-Techne | Catalog # H00002268-M03

Novus Biologicals, part of Bio-Techne
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H00002268-M03
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human

Applications

Validated:

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 1B12

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Fgr Antibodies »

Product Specifications

Immunogen

FGR (AAH64382, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MGCVFCKKLEPVATAKEDAGLEGDFRSYGAADHYGPDPTKARPASSFAHIPNYSNFSSQAINPGFLDSGTIRGVSGIGVTLFIALYDYEA

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Specificity

FGR - Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Fgr Antibody (1B12)

Western Blot: Fgr Antibody (1B12) [H00002268-M03]

Western Blot: Fgr Antibody (1B12) [H00002268-M03]

Western Blot: Fgr Antibody (1B12) [H00002268-M03] - Analysis of FGR expression in transfected 293T cell line by FGR monoclonal antibody (M03), clone 1B12. Lane 1: FGR transfected lysatE (59.5 KDa). Lane 2: Non-transfected lysate.
Immunohistochemistry-Paraffin: Fgr Antibody (1B12) [H00002268-M03]

Immunohistochemistry-Paraffin: Fgr Antibody (1B12) [H00002268-M03]

Immunohistochemistry-Paraffin: Fgr Antibody (1B12) [H00002268-M03] - Analysis of monoclonal antibody to FGR on formalin-fixed paraffin-embedded human spleen. Antibody concentration 3 ug/ml
Western Blot: Fgr Antibody (1B12) [H00002268-M03]

Western Blot: Fgr Antibody (1B12) [H00002268-M03]

Western Blot: Fgr Antibody (1B12) [H00002268-M03] - Analysis of FGR expression in HeLa (Cat # L013V1).
View 3 more images

Applications for Fgr Antibody (1B12)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IHC-P and ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Fgr

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Long Name

Gardner-Rasheed Feline Sarcoma Viral Oncogene Homolog

Alternate Names

Src2

Entrez Gene IDs

2268 (Human)

Gene Symbol

FGR

OMIM

164940 (Human)

UniProt

AAH64382 (Human)

Additional Fgr Products

Product Documents for Fgr Antibody (1B12)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Fgr Antibody (1B12)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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