Fibrillin 1 Antibody (3H6)

Novus Biologicals, part of Bio-Techne | Catalog # H00002200-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 3H6

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Fibrillin-1/FBN1 Antibodies »

Product Specifications

Immunogen

FBN1 (NP_000129, 2772 a.a. ~ 2871 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. SNKVRILELLPALTTLTNHNRYLIESGNEDGFFKINQKEGISYLHFTKKKPVAGTYSLQISSTPLYKKKELNQLEDKYDKDYLSGELGDNLKMKIQVLLH

Specificity

FBN1 - fibrillin 1 (Marfan syndrome)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Fibrillin 1 Antibody (3H6)

Immunohistochemistry-Paraffin: Fibrillin 1 Antibody (3H6) [H00002200-M01]

Immunohistochemistry-Paraffin: Fibrillin 1 Antibody (3H6) [H00002200-M01]

Immunohistochemistry-Paraffin: Fibrillin 1 Antibody (3H6) [H00002200-M01] - Analysis of monoclonal antibody to FBN1 on formalin-fixed paraffin-embedded human kidney. Antibody concentration 3 ug/ml.
Sandwich ELISA: Fibrillin 1 Antibody (3H6) [H00002200-M01] - Detection limit for recombinant GST tagged FBN1 is 0.3 ng/ml as a capture antibody.

Applications for Fibrillin 1 Antibody (3H6)

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Sandwich ELISA

1:100-1:2000

Western Blot

1:500
Application Notes
Antibody reactivity against recombinant protein for WB. It has been used for IHC-P and ELISA.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Fibrillin-1/FBN1

This gene encodes a member of the fibrillin family. The encoded protein is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome.

Long Name

Fibrillin-1

Alternate Names

ACMICD, Asprosin, Fibrillin 1, GPHYSD2, SSKS, WMS2

Entrez Gene IDs

2200 (Human)

Gene Symbol

FBN1

OMIM

129600 (Human)

UniProt

NP_000129 (Human)

Additional Fibrillin-1/FBN1 Products

Product Documents for Fibrillin 1 Antibody (3H6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Fibrillin 1 Antibody (3H6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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