Fibrinogen gamma chain Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87448

Novus Biologicals, part of Bio-Techne
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NBP1-87448
NBP1-87448-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Fibrinogen gamma chain Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MIDAATLKSRKMLEEIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEF

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (87%), Rat (86%). Reactivity reported in scientific literature (PMID: 24648543)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Fibrinogen gamma chain Antibody

Immunohistochemistry: Fibrinogen gamma chain Antibody [NBP1-87448]

Immunohistochemistry: Fibrinogen gamma chain Antibody [NBP1-87448]

Immunohistochemistry: Fibrinogen gamma chain Antibody [NBP1-87448] - Staining of human gall bladder shows distinct positivity in plasma.

Applications for Fibrinogen gamma chain Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Fibrinogen gamma chain

The protein encoded by the Fibrinogen gamma chain gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.

Alternate Names

fibrinogen gamma chain, fibrinogen, gamma polypeptide

Gene Symbol

FGG

Additional Fibrinogen gamma chain Products

Product Documents for Fibrinogen gamma chain Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Fibrinogen gamma chain Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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