Key Product Details

Species Reactivity

Human

Applications

Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # 49D2

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Fibrinogen A Antibodies »

Product Specifications

Immunogen

Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with Fibrinopeptide A conjugated with a carrier protein.

Specificity

Fibrinopeptide A region in the alpha-chain of fibrinogen and free fibrinopeptide A.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for Fibrinopeptide A Antibody (49D2)

Application
Recommended Usage

Sandwich ELISA

1:100-1:2000

Western Blot

1:500-1:2000
Application Notes
Fibrinogen and fibrinopeptide A immunoassay. For specific fibrinogen detection in sandwich ELISA we recommend using anti-fibrinopeptide A MAbs for coating and anti-fibrinogen MAbs for conjugation. Recommended pairs for sandwich immunoassay (capture-detection): NB100-73043 - NB120-10068

Reviewed Applications

Read 1 review rated 4 using NB100-73043 in the following applications:

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

0.09% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Fibrinogen A

Fibrinogen is the main protein of the blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A and B are released by thrombin from the N terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerisation forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases.

Alternate Names

FGA, Fib2, Fibrinogen alpha chain, Fibrinogen alpha subunit, Fibrinogen Type I, FPA

Entrez Gene IDs

2243 (Human); 238644 (Mouse)

Gene Symbol

FGA

Additional Fibrinogen A Products

Product Documents for Fibrinopeptide A Antibody (49D2)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Fibrinopeptide A Antibody (49D2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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