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FKBP6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-54606

Novus Biologicals, part of Bio-Techne
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NBP1-54606

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

Product Specifications

Immunogen

Synthetic peptides corresponding to FKBP6(FK506 binding protein 6, 36kDa) The peptide sequence was selected from the middle region of FKBP6. Peptide sequence FCALSAEQQDQFPLQKVLKVAATEREFGNYLFRQNRFYDAKVRYKRALLL. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for FKBP6 Antibody

Western Blot: FKBP6 Antibody [NBP1-54606]

Western Blot: FKBP6 Antibody [NBP1-54606]

Western Blot: FKBP6 Antibody [NBP1-54606] - Titration: 1.25ug/ml Positive Control: HepG2 cell lysate.
Immunohistochemistry-Paraffin: FKBP6 Antibody [NBP1-54606]

Immunohistochemistry-Paraffin: FKBP6 Antibody [NBP1-54606]

Immunohistochemistry-Paraffin: FKBP6 Antibody [NBP1-54606] - Human kidney Tissue, antibody concentration 4-8ug/ml. Cells with positive label: renal corpuscle cells (indicated with arrows) 400X magnification.

Applications for FKBP6 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FKBP6

FKBP6 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP6 is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin.This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.

Alternate Names

36 kDa FKBP, EC 5.2.1.8, FK506 binding protein 6, 36kDa, FK506-binding protein 6, FK506-binding protein 6 (36kD), FKBP-36, FKBP36MGC87179, FKBP-6, Immunophilin FKBP36, peptidyl-prolyl cis-trans isomerase FKBP6,36 kDa FK506-binding protein, PPIase, PPIase FKBP6, Rotamase

Gene Symbol

FKBP6

UniProt

Additional FKBP6 Products

Product Documents for FKBP6 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for FKBP6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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