FLIP Antibody (NF6) [Janelia Fluor® 646]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-80081JF646

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP2-80081AF350

Alexa Fluor 405

NBP2-80081AF405

Alexa Fluor 488

NBP2-80081AF488

Alexa Fluor 532

NBP2-80081AF532

Alexa Fluor 594

NBP2-80081AF594

Alexa Fluor 647

NBP2-80081AF647

Alexa Fluor 700

NBP2-80081AF700

Alexa Fluor 750

NBP2-80081AF750

Allophycocyanin

NBP2-80081APC

Biotin

NBP2-80081B

CoraFluor 1

NBP2-80081CL1

DyLight 350

NBP2-80081UV

DyLight 405

NBP2-80081V

DyLight 488

NBP2-80081G

DyLight 550

NBP2-80081R

DyLight 594

NBP2-80081DL594

DyLight 650

NBP2-80081C

DyLight 680

NBP2-80081FR

DyLight 755

NBP2-80081IR

FITC

NBP2-80081F

HRP

NBP2-80081H

Janelia Fluor 525

NBP2-80081JF525

Janelia Fluor 549

NBP2-80081JF549

Janelia Fluor 585

NBP2-80081JF585

Janelia Fluor 635

NBP2-80081JF635

Janelia Fluor 669

NBP2-80081JF669

PE

NBP2-80081PE

PerCP

NBP2-80081PCP

Forumulation

Catalog #

BSA Free

NBP2-80081

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Janelia Fluor 646

Antibody Source

Monoclonal Mouse IgG₁ Clone # NF6

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all FLIP Antibodies »

Product Summary for FLIP Antibody (NF6) [Janelia Fluor® 646]

Immunogen

Recombinant human FLIP (aa 1-480).

Specificity

Recognizes short (FLIPS) and long (FLIPL) splice variants of human FLIP. This antibody recognizes an epitope in the N-terminal DED region (aa1-194).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Applications for FLIP Antibody (NF6) [Janelia Fluor® 646]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

>95%, by SDS-PAGE

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: FLIP

Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity

Long Name

FLICE Inhibitory Proteins

Alternate Names

CASPER, CFLAR, FLAME-1, I-FLICE

Gene Symbol

CFLAR

Additional FLIP Products

Product Documents for FLIP Antibody (NF6) [Janelia Fluor® 646]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for FLIP Antibody (NF6) [Janelia Fluor® 646]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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