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Flt-3/Flk-2/CD135 Antibody (7B7C3) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-37363

Novus Biologicals, part of Bio-Techne
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NBP2-37363
NBP2-37363-0.025ml

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 7B7C3

Format

BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

Purified recombinant fragment of human Flt-3/Flk-2/CD135 (AA: 930-991) expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

130 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Flt-3/Flk-2/CD135 Antibody (7B7C3) - BSA Free

Western Blot: Flt-3/Flk-2/CD135 Antibody (7B7C3)BSA Free [NBP2-37363]

Western Blot: Flt-3/Flk-2/CD135 Antibody (7B7C3)BSA Free [NBP2-37363]

Western Blot: Flt-3/Flk-2/CD135 Antibody (7B7C3) [NBP2-37363] - Analysis using FLT3 mAb against human FLT3 recombinant protein. (Expected MW is 32.6 kDa)
Immunohistochemistry-Paraffin: Flt-3/Flk-2/CD135 Antibody (7B7C3) - BSA Free [NBP2-37363]

Immunohistochemistry-Paraffin: Flt-3/Flk-2/CD135 Antibody (7B7C3) - BSA Free [NBP2-37363]

Immunohistochemistry-Paraffin: Flt-3/Flk-2/CD135 Antibody (7B7C3) [NBP2-37363] - Analysis of liver cancer tissues using FLT3 mouse mAb with DAB staining.
Immunohistochemistry-Paraffin: Flt-3/Flk-2/CD135 Antibody (7B7C3) - BSA Free [NBP2-37363]

Immunohistochemistry-Paraffin: Flt-3/Flk-2/CD135 Antibody (7B7C3) - BSA Free [NBP2-37363]

Immunohistochemistry-Paraffin: Flt-3/Flk-2/CD135 Antibody (7B7C3) [NBP2-37363] - Analysis of cervical cancer tissues using FLT3 mouse mAb with DAB staining.

Applications for Flt-3/Flk-2/CD135 Antibody (7B7C3) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Immunohistochemistry

1:200 - 1:1000

Immunohistochemistry-Paraffin

1:200 - 1:1000

Western Blot

1:500 - 1:2000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Flt-3/Flk-2

Stem cell tyrosine kinase (STK-1) has been cloned from a CD34+ hematopoietic stem cell enriched library and identified as the human homolog of a previously identified gene of mouse origin designated either Flk-2 or Flt-3. The STK-1 cDNA encodes a protein of 993 amino acids with 85% identity to Flt-3/Flk-2. STK-1 is a member of the type III receptor tyrosine kinase family that includes Kit (steel factor receptor), Fms and PDGF. STK-1 expression in blood and marrow is restricted to CD34+ cells, a population greatly enriched for hematopoietic stem/progenitor cells. STK-1 antiserum recognizes two polypeptides in these cells. The mouse homolog of STK-1, designated Flt-3/ Flk-2, is expressed at high levels in hematopoietic cells and also in neural, gonadal, hepatic and placental tissues. It has been suggested that STK-1 and its murine homolog Flt-3/ Flk-2 may function as growth factor receptors on hematopoietic stem and/or progenitor cells.

Long Name

fms-like Tyrosine Kinase 3

Alternate Names

CD135, Flk-2, Flt3, STK-1

Gene Symbol

FLT3

Additional Flt-3/Flk-2 Products

Product Documents for Flt-3/Flk-2/CD135 Antibody (7B7C3) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Flt-3/Flk-2/CD135 Antibody (7B7C3) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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