Flt-3/Flk-2 Products
The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and STK-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes c-kit, the receptor for SCF, and fms, the receptor for M-CSF. Mouse Flt-3 shares 85% amino acid sequence identity with human Flt-3. Flt-3 expression has been detected in various tissues, including placenta, gonads, and tissues of nervous and hematopoietic origin.
264 results for "Flt-3/Flk-2" in Products
264 results for "Flt-3/Flk-2" in Products
Flt-3/Flk-2 Products
The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and STK-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes c-kit, the receptor for SCF, and fms, the receptor for M-CSF. Mouse Flt-3 shares 85% amino acid sequence identity with human Flt-3. Flt-3 expression has been detected in various tissues, including placenta, gonads, and tissues of nervous and hematopoietic origin.
Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies
Potent FLT3 inhibitor; also potently inhibits AXL
| Chemical Name: | 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA, Flow, CyTOF-ready |
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
| Alternate Names: | Semaxinib |
| Chemical Name: | 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one |
| Purity: | ≥99% (HPLC) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #66903 |
| Applications: | Flow, CyTOF-ready |
Contains 4 membranes - each spotted in duplicate with 39 different RTK antibodies
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1038631 |
| Applications: | IHC |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #113308 |
| Applications: | Flow, CyTOF-ready, ICC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, Simple Western, ICC |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #12B6 |
| Applications: | IHC, WB |
![Immunohistochemistry-Paraffin: Flt-3/Flk-2/CD135 Antibody (12B6) - Azide and BSA Free [NB110-94155]](https://resources.bio-techne.com/images/products/Flt-3-Flk-2-CD135-Antibody-12B6-Immunohistochemistry-Paraffin-NB110-94155-img0003.jpg "Immunohistochemistry-Paraffin: Flt-3/Flk-2/CD135 Antibody (12B6) - Azide and BSA Free [NB110-94155]")
| Source: | HEK293 |
| Accession #: | P36888 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | Q00342 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | AAA18947 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, CyTOF-ready |
Biotinylated
| Source: | CHO |
| Accession #: | P36888.2 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #66907 |
| Applications: | WB, ELISA |
| Assay Range: | 125 - 8,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG2b Lambda Monoclonal Clone #7E8.2C8 |
| Applications: | IHC, WB, Flow |
![Western Blot: Flt-3/Flk-2/CD135 Antibody (7E8.2C8)BSA Free [NBP2-42210]](https://resources.bio-techne.com/images/products/Flt-3-Flk-2-CD135-Antibody-7E8-2C8-Western-Blot-NBP2-42210-img0001.jpg "Western Blot: Flt-3/Flk-2/CD135 Antibody (7E8.2C8)BSA Free [NBP2-42210]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #66903 |
| Applications: | Flow |
JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB
| Alternate Names: | CEP-701 |
| Chemical Name: | (9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #66903 |
| Applications: | Flow |
Highly potent ALK inhibitor; also potently inhibits IR, IGF1R, STK22D and FLT3
| Alternate Names: | LDK378 |
| Chemical Name: | 5-Chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine |
| Purity: | ≥98% (HPLC) |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #113315 |
| Applications: | WB |