FMN2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-24615

Novus Biologicals, part of Bio-Techne
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NBP2-24615
NBP2-24615SS
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all FMN2 Antibodies »

Product Specifications

Immunogen

A synthetic peptide corresponding to amino acids 657-688 of human FMN2 was used as immunogen, Gene Bank no NP_064450.3.

Reactivity Notes

Mouse, Rat (77%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FMN2 Antibody

Western Blot: FMN2 Antibody [NBP2-24615]

Western Blot: FMN2 Antibody [NBP2-24615]

Western Blot: FMN2 Antibody [NBP2-24615] - Analysis of FMN2 in human brain lysate in the 1) absence and 2) presence of immunizing peptide using NBP2-24615 at 0.25 ug/ml.
Immunohistochemistry-Paraffin: FMN2 Antibody [NBP2-24615]

Immunohistochemistry-Paraffin: FMN2 Antibody [NBP2-24615]

Immunohistochemistry-Paraffin: FMN2 Antibody [NBP2-24615] - Tissue section of human brain using 1:300 dilution of FMN2 antibody. The signal was developed using HRP-labeled secondary and DAB reagent which followed counterstaining of nuclei with hematoxylin. This FMN2 antibody generated a nuclear and cytoplasmic staining primarily in the glial cells.

Applications for FMN2 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:300-1:500

Western Blot

1:100-1:4000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.1 ml PBS

Preservative

0.05% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FMN2

The FMN2 gene encodes a 1,722 amino acid long, 180 kDA formin-2 protein that is essential in cytoskeletal organization as well as establishment of cell polarity, particularly during female germ cell meiosis. This gene reacts to responses in DNA damage, cellular stress, and hypoxia. Additionally, it protects cells against apoptosis by protecting CDKN1A against degradation. FMN2 participates in dorso-ventral axis formation and interacts with the SPIRE1 gene. It has been associated with infertility, coronary heart disease, multiple sclerosis, atherosclerosis, and aortic aneurysms.

Alternate Names

formin 2

Gene Symbol

FMN2

Additional FMN2 Products

Product Documents for FMN2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FMN2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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