FOXL1 Antibody (1C3)

Novus Biologicals, part of Bio-Techne | Catalog # H00002300-M04

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 1C3

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all FOXL1 Antibodies »

Product Specifications

Immunogen

FOXL1 (NP_005241, 132 a.a. ~ 240 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MFENGNYRRRKRKPKPGPGAPEAKRPRAETHQRSAEAQPEAGSGAGGSGPAISRLQAAPAGPSPLLDGPSPPAPLHWPGTASPNEDAGDAAQGAAAVAVGQAARTGDGP

Specificity

FOXL1 (1C3)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for FOXL1 Antibody (1C3)

Immunohistochemistry-Paraffin: FOXL1 Antibody (1C3) [H00002300-M04]

Immunohistochemistry-Paraffin: FOXL1 Antibody (1C3) [H00002300-M04]

Immunohistochemistry-Paraffin: FOXL1 Antibody (1C3) [H00002300-M04] - Analysis of monoclonal antibody to FOXL1 on formalin-fixed paraffin-embedded human lung. Antibody concentration 3 ug/ml

Applications for FOXL1 Antibody (1C3)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against recombinant protein with GST tag on ELISA and WB. It has been used for IHC-P.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: FOXL1

FOXL1 is a 337 amino acid protein encoded by the mouse gene Foxl1. FOXL1 belongs to the fork head family and contains one fork head DNA-binding domain. The HNF3/fork head family includes a large number of transcription factors that share a structurally related DNA binding domain. Fork head factors are known to play important roles both during development and in adults. FOXL1 is a winged helix transcriptional regulator expressed in the mesenchymal layer of developing and mature gastrointestinal tract. FOXL1- deficient mice exhibit various defects not only in the epithelial layer of the gastrointestinal tract but also in gut-associated lymphoid tissues. In the small intestine of FOXL1-deficient mice, the formation of Peyer's patches is affected, particularly in the caudal region. FOXL1 is a mesenchymal modifier of the adenomatous polyposis coli (APC) gene products and plays a key role in gastrointestinal tumorigenesis.

Alternate Names

FKH6forkhead box protein L1, FKHL11forkhead-like 11, forkhead box L1, Forkhead-related protein FKHL11, Forkhead-related transcription factor 7, FREAC7FREAC-7

Entrez Gene IDs

2300 (Human)

Gene Symbol

FOXL1

OMIM

603252 (Human)

UniProt

NP_005241 (Human)

Additional FOXL1 Products

Product Documents for FOXL1 Antibody (1C3)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for FOXL1 Antibody (1C3)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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