FoxP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-51907

Novus Biologicals, part of Bio-Techne
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NBP1-51907
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Key Product Details

Species Reactivity

Human

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all FoxP2 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-REIEEEPLSEDLE corresponding to C-Terminus according to NP_055306.1, NP_683696.2, NP_683697.1.

Epitope

C-REIEEEPLSEDLE

Reactivity Notes

Expected from sequence similarity: Mouse, Rat, Canine, Porcine, Bovine

Specificity

This antibody is expected to recognise all three reported isoforms (NP_055306.1; NP_683696.2; NP_683697.1).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for FoxP2 Antibody

Western Blot: FoxP2 Antibody [NBP1-51907]

Western Blot: FoxP2 Antibody [NBP1-51907]

Western Blot: FoxP2 Antibody [NBP1-51907] - Staining of Human Cerebellum lysate (35 ug protein in RIPA buffer). Antibody at 2 ug/mL. Detected by chemiluminescence. Approx 80-90 kDa band observe (calculated MW of 82.6 kDa according to NP_683696.2).

Applications for FoxP2 Antibody

Application
Recommended Usage

Peptide ELISA

1:128000

Western Blot

0.5 - 2 ug/mL
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: FoxP2

This gene encodes an evolutionarily conserved transcription factor expressed in fetal and adult brain. This transcription factor is a member of the forkhead/winged-helix (FOX) family of transcription factors, and contains a FOX DNA-binding domain and a large polyglutamine tract. Members of the FOX family of transcription factors are regulators of embryogenesis. The product of this gene is thought to be required for proper development of speech and language regions of the brain during embryogenesis. Although a point mutation in this gene has been associated with the KE pedigree segregating developmental verbal dyspraxia, no association between mutations in this gene and another speech disorder, autism, has been found. Multiple alternative transcripts encoding different isoforms have been identified. [provided by RefSeq]

Long Name

Forkhead Box P2

Alternate Names

CAGH44, SPCH1, TNRC10

Entrez Gene IDs

93986 (Human)

Gene Symbol

FOXP2

UniProt

NP_055306.1 (Human)

Additional FoxP2 Products

Product Documents for FoxP2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FoxP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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