FPR1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-47452

Novus Biologicals, part of Bio-Techne
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NBP2-47452
NBP2-47452-25ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all FPR1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: TTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLT

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 29057162).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FPR1 Antibody

Immunohistochemistry-Paraffin: FPR1 Antibody [NBP2-47452]

Immunohistochemistry-Paraffin: FPR1 Antibody [NBP2-47452]

Immunohistochemistry-Paraffin: FPR1 Antibody [NBP2-47452] - Staining of human tonsil shows weak cytoplasmic positivity in non-germinal center cells.
Immunohistochemistry-Paraffin: FPR1 Antibody [NBP2-47452]

Immunohistochemistry-Paraffin: FPR1 Antibody [NBP2-47452]

Immunohistochemistry-Paraffin: FPR1 Antibody [NBP2-47452] - Staining of human colon tissue. Shows moderate cytoplasmic positivity in glandular cells and strong cytoplasmic positivity in peripheral leukocytes.
Immunohistochemistry-Paraffin: FPR1 Antibody [NBP2-47452]

Immunohistochemistry-Paraffin: FPR1 Antibody [NBP2-47452]

Immunohistochemistry-Paraffin: FPR1 Antibody [NBP2-47452] - Staining of human liver shows no positivity in hepatocytes as expected.
View 1 more images

Applications for FPR1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Reported in scientific literature (PMID : 29057162)

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Reviewed Applications

Read 1 review rated 5 using NBP2-47452 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FPR1

Official Gene Symbol: FPR1 Gen Bank Accession Number: NP_002020 Gene ID: 2357 (Human) Gene Map Locus: 19q13.4 (Human) FPR1 is a member of chemoattractant/chemokine GPCRs expressed mainly on leukocytes, neutrophils and monocytes. FPR1 is a seven transmembrane pertussis toxin-sensitive GPCR and binds to formylated peptides generated by bacteria resulting in leukocyte trafficking to the site of inflammation. Ligand binding to FPR results in activation of multiple effectors including phospholipase C leading to calcium mobilization and PKC activation. Other implications of FPR signaling include polarization of actin cytoskeletion, activation of various integrins, increased cell migration, phagocytosis, degranulation and release of reactive oxygen intermediates.

Long Name

Formyl Peptide Receptor 1

Alternate Names

fMLF-R, FMLP

Gene Symbol

FPR1

Additional FPR1 Products

Product Documents for FPR1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FPR1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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