FPR1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14321

Novus Biologicals, part of Bio-Techne
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NBP3-14321
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Chimpanzee (100%), Primate (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

1 mg/ml

View all FPR1 Antibodies »

Product Specifications

Immunogen

Synthetic 18 amino acid peptide from 3rd extracellular domain of human FPR1.

Epitope

Extracellular Domain

Reactivity Notes

Expected reactivity based on percent sequence identity: Gibbon (83%)

Specificity

Human FPR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for FPR1 Antibody

Immunohistochemistry-Paraffin: FPR1 Antibody [NBP3-14321]

Immunohistochemistry-Paraffin: FPR1 Antibody [NBP3-14321]

Immunohistochemistry-Paraffin: FPR1 Antibody [NBP3-14321] - Immunohistochemistry of formalin-fixed, paraffin-embedded human spleen, red pulp, after heat-induced antigen retrieval.

Applications for FPR1 Antibody

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.1% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: FPR1

Official Gene Symbol: FPR1 Gen Bank Accession Number: NP_002020 Gene ID: 2357 (Human) Gene Map Locus: 19q13.4 (Human) FPR1 is a member of chemoattractant/chemokine GPCRs expressed mainly on leukocytes, neutrophils and monocytes. FPR1 is a seven transmembrane pertussis toxin-sensitive GPCR and binds to formylated peptides generated by bacteria resulting in leukocyte trafficking to the site of inflammation. Ligand binding to FPR results in activation of multiple effectors including phospholipase C leading to calcium mobilization and PKC activation. Other implications of FPR signaling include polarization of actin cytoskeletion, activation of various integrins, increased cell migration, phagocytosis, degranulation and release of reactive oxygen intermediates.

Long Name

Formyl Peptide Receptor 1

Alternate Names

fMLF-R, FMLP

Gene Symbol

FPR1

Additional FPR1 Products

Product Documents for FPR1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for FPR1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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