GABA-A R beta 3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-10888

Novus Biologicals, part of Bio-Techne
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NBP3-10888-100ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all GABA-A R beta 3 Antibodies »

Product Summary for GABA-A R beta 3 Antibody

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human GABA-A R beta 3 (NP_068712). Peptide sequence DIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSF

Clonality

Polyclonal

Host

Rabbit

Theoretical MW

52 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GABA-A R beta 3 Antibody

Western Blot: GABA-A R beta 3 Antibody [NBP3-10888]

Western Blot: GABA-A R beta 3 Antibody [NBP3-10888]

Western Blot: GABA-A R beta 3 Antibody [NBP3-10888] - Western blot analysis of GABA-A R beta 3 in Esophagus Tumor lysates. Antibody dilution at 1.0ug/ml

Applications for GABA-A R beta 3 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GABA-A R beta 3

The GABRB3 gene encodes a member of the ligand-gated ionic channel family. The encoded protein, GABA A Receptor beta 3, is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. GABRB3 is located on the long arm of chromosome 15 in a cluster with two genes encoding related subunits of the family. Mutations in the GABA A Receptor beta 3 gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism.

Long Name

gamma-Aminobutyric Acid Type A Receptor, beta-3 Polypeptide

Alternate Names

GABAAR beta 3, GABAARb3, GABRB3

Gene Symbol

GABRB3

Additional GABA-A R beta 3 Products

Product Documents for GABA-A R beta 3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GABA-A R beta 3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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