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GADD45 alpha Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-55059

Novus Biologicals, part of Bio-Techne
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NBP2-55059
NBP2-55059-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (91%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for GADD45 alpha Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQ

Reactivity Notes

Rat 88%

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GADD45 alpha Antibody

Immunocytochemistry/ Immunofluorescence: GADD45 alpha Antibody [NBP2-55059]

Immunocytochemistry/ Immunofluorescence: GADD45 alpha Antibody [NBP2-55059]

Immunocytochemistry/Immunofluorescence: GADD45 alpha Antibody [NBP2-55059] - Staining of human cell line PC-3 shows localization to nuclear speckles.

Applications for GADD45 alpha Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GADD45 alpha

GADD45A is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. [provided by RefSeq]

Long Name

Growth Arrest and DNA Damage Gene alpha

Alternate Names

GADD45a

Gene Symbol

GADD45A

Additional GADD45 alpha Products

Product Documents for GADD45 alpha Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GADD45 alpha Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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