GAK Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89441

Novus Biologicals, part of Bio-Techne
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NBP1-89441
NBP1-89441-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (98%), Rat (98%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GAK Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: VLAEGGFAFVYEAQDVGSGREYALKRLLSNEEEKNRAIIQEVCFMKKLSGHPNIVQFCSAASIGKEESDTGQAEFLLLTELCKGQLVE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GAK Antibody

Immunocytochemistry/ Immunofluorescence: GAK Antibody [NBP1-89441]

Immunocytochemistry/ Immunofluorescence: GAK Antibody [NBP1-89441]

Immunocytochemistry/Immunofluorescence: GAK Antibody [NBP1-89441] - Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus & vesicles. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: GAK Antibody [NBP1-89441]

Immunohistochemistry-Paraffin: GAK Antibody [NBP1-89441]

Immunohistochemistry-Paraffin: GAK Antibody [NBP1-89441] - Staining of human Skeletal muscle shows no granular cytoplasmic positivity in myocytes.
Immunohistochemistry-Paraffin: GAK Antibody [NBP1-89441]

Immunohistochemistry-Paraffin: GAK Antibody [NBP1-89441]

Immunohistochemistry-Paraffin: GAK Antibody [NBP1-89441] - Staining of human prostate shows strong cytoplasmic positivity in glandular cells.
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Applications for GAK Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20-1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GAK

In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5.

Long Name

Cyclin G-associated Kinase

Alternate Names

Auxillin 2

Gene Symbol

GAK

Additional GAK Products

Product Documents for GAK Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GAK Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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