gamma C Crystallin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-32557

Novus Biologicals, part of Bio-Techne
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NBP1-32557
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Chimpanzee (99%), Rhesus Macaque (96%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all gamma C Crystallin Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human gamma C Crystallin. The exact sequence is proprietary.

Reactivity Notes

Bovine (85%), Guinea pig (86%), Mouse (84%), Rat (85%), Dog (87%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

21 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for gamma C Crystallin Antibody

Western Blot: gamma C Crystallin Antibody [NBP1-32557]

Western Blot: gamma C Crystallin Antibody [NBP1-32557]

Western Blot: gamma C Crystallin Antibody [NBP1-32557] - Various tissue extracts (50 ug) were separated by 15% SDS-PAGE, and the membrane was blotted with gamma C Crystallin antibody diluted at 1:20000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
Western Blot: gamma C Crystallin Antibody [NBP1-32557]

Western Blot: gamma C Crystallin Antibody [NBP1-32557]

Western Blot: gamma C Crystallin Antibody [NBP1-32557] - (30 ug whole cell lysate) A:A431 12% SDS PAGE diluted at 1:1000

Applications for gamma C Crystallin Antibody

Application
Recommended Usage

Western Blot

1:500-1:20000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: gamma C Crystallin

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. [provided by RefSeq]

Alternate Names

CCL, CRYG3gamma-C-crystallin, crystallin, gamma C, crystallin, gamma-3, Gamma-C-crystallin, Gamma-crystallin 2-1, Gamma-crystallin 3, gamma-crystallin C

Gene Symbol

CRYGC

Additional gamma C Crystallin Products

Product Documents for gamma C Crystallin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for gamma C Crystallin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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