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Gas1 Antibody (11C47) [CoraFluor™ 1]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-22032CL1

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

CoraFluor 1

Antibody Source

Monoclonal Rat IgG2 Clone # 11C47

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Human recombinant Gas1

Clonality

Monoclonal

Host

Rat

Isotype

IgG2

Description

CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.

Applications for Gas1 Antibody (11C47) [CoraFluor™ 1]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: Gas1

The growth arrest-specific genes are related by their induction following cellular stress. Gas1 is a GPI-linked membrane glycoprotein that blocks entry to S phase cell cycle. Gas1 inhibits cell proliferation, protects endothelial cells from apoptosis, and promotes excitotoxic neuronal death. Gas6 is a vitamin K-dependent protein with a gamma-carboxylated amino terminus (Gla domain), four EGF-like repeats, and C-terminal globulin-like domains. Gas6 is a ligand for the Axl, Dtk, and Mer tyrosine kinase receptors. Gas6 is mitogenic and anti-apoptotic for some cell types and also promotes cell adhesion.

Long Name

Growth-arrest-specific Protein 1

Alternate Names

GAS-1, growth arrest-specific 1, Growth arrest-specific gene-1, growth arrest-specific protein 1

Gene Symbol

GAS1

Additional Gas1 Products

Product Documents for Gas1 Antibody (11C47) [CoraFluor™ 1]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Gas1 Antibody (11C47) [CoraFluor™ 1]

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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