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GCLM Antibody (GCLM/4069)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-23896

Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-23896-100ug
NBP3-23896-20ug

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # GCLM/4069

Concentration

0.2 mg/ml

Product Summary for GCLM Antibody (GCLM/4069)

Immunogen

Recombinant full-length human GCLM protein

Localization

Nucleus.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Store at 2 to 8C. Non-hazardous. No MSDS required.

Scientific Data Images for GCLM Antibody (GCLM/4069)

GCLM Antibody (GCLM/4069)

Immunohistochemistry-Paraffin: GCLM Antibody (GCLM/4069) [NBP3-23896] -

Formalin-fixed, paraffin-embedded human ovarian cancer stained with GCLM antibody (GCLM/4069). Inset: PBS instead of primary antibody; secondary only negative control.

Applications for GCLM Antibody (GCLM/4069)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2ug/ml
Application Notes
Immunohistochemistry-Paraffin: 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: GCLM

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. [provided by RefSeq]

Alternate Names

Gamma-ECS regulatory subunit, Gamma-glutamylcysteine synthetase regulatory subunit, GCS light chain, GLCLRglutamate--cysteine ligase regulatory subunit, glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory(30.8kD), Glutamate--cysteine ligase modifier subunit, glutamate-cysteine ligase regulatory protein, glutamate-cysteine ligase, modifier subunit, GSC light chain

Gene Symbol

GCLM

Additional GCLM Products

Product Documents for GCLM Antibody (GCLM/4069)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GCLM Antibody (GCLM/4069)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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