GFR alpha-4/GDNF R alpha-4/Persephin receptor Antibody (MM0311-3P34) [PE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-12414PE

Submit a review

Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP2-12414AF350

Alexa Fluor 405

NBP2-12414AF405

Alexa Fluor 488

NBP2-12414AF488

Alexa Fluor 532

NBP2-12414AF532

Alexa Fluor 594

NBP2-12414AF594

Alexa Fluor 647

NBP2-12414AF647

Alexa Fluor 700

NBP2-12414AF700

Alexa Fluor 750

NBP2-12414AF750

Allophycocyanin

NBP2-12414APC

Biotin

NBP2-12414B

CoraFluor 1

NBP2-12414CL1

DyLight 350

NBP2-12414UV

DyLight 405

NBP2-12414V

DyLight 488

NBP2-12414G

DyLight 550

NBP2-12414R

DyLight 594

NBP2-12414DL594

DyLight 650

NBP2-12414C

DyLight 680

NBP2-12414FR

DyLight 755

NBP2-12414IR

FITC

NBP2-12414F

HRP

NBP2-12414H

Janelia Fluor 525

NBP2-12414JF525

Janelia Fluor 549

NBP2-12414JF549

Janelia Fluor 585

NBP2-12414JF585

Janelia Fluor 635

NBP2-12414JF635

Janelia Fluor 646

NBP2-12414JF646

Janelia Fluor 669

NBP2-12414JF669

mFluor Violet 450 SE

NBP2-12414MFV450

mFluor Violet 500 SE

NBP2-12414MFV500

mFluor Violet 610 SE

NBP2-12414MFV610

PerCP

NBP2-12414PCP

Forumulation

Catalog #

Azide and BSA Free

NBP2-12414

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Monoclonal Mouse IgG₁ Clone # MM0311-3P34

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all GFR alpha-4/GDNF R alpha-4 Antibodies »

Product Specifications

Immunogen

Human recombinant GFR alpha-4/GDNF R alpha-4/Persephin receptor

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Applications

Application

Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: GFR alpha-4/GDNF R alpha-4

Glial cell line-derived neurotrophic factor (GDNF) and the related neurotrophic factor neurturin (NTN) are potent survival factors for central and peripheral neurons. Receptors for these factors include GFRalpha-1 (previously designated GDNFR-alpha), GFRalpha-2 (also designated RETL2), GFRalpha-3 and GFRalpha-4 (also known as persephin receptor). The receptors do not contain transmembrane domains and are attached to the cell membrane by glycosylphosphoinositol linkage. Binding of GDNF or NTN to one of these receptors leads to the activation of the tyrosine kinase Ret. GFRalpha-4 mediates the activation and GDNF-induced autophosphorylation of the RET receptor. It is mainly expressed in the adult thyroid gland, but lower levels may also be detected in fetal adrenal and thyroid glands.

Long Name

Glial Cell line-derived Neurotrophic Factor Receptor alpha 4

Alternate Names

GDNF R alpha-4, GFR alpha4, GFRa-4, GFRA4

Gene Symbol

GFRA4

Additional GFR alpha-4/GDNF R alpha-4 Products

Product Documents

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews