GGPS1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-53050

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all GGPS1 Antibodies »

Product Summary for GGPS1 Antibody

Immunogen

Synthetic peptides corresponding to GGPS1(geranylgeranyl diphosphate synthase 1) The peptide sequence was selected from the middle region of GGPS1 (NP_001032354). Peptide sequence LGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIWSRPESTQ. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

35 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for GGPS1 Antibody

Western Blot: GGPS1 Antibody [NBP1-53050]

Western Blot: GGPS1 Antibody [NBP1-53050]

Western Blot: GGPS1 Antibody [NBP1-53050] - 293T cells lysate, concentration 0.2-1 ug/ml.

Immunohistochemistry-Paraffin: GGPS1 Antibody [NBP1-53050] -

Immunohistochemistry-Paraffin: GGPS1 Antibody [NBP1-53050] - Formalin Fixed Paraffin; Embedded Tissue: Human Pineal Tissue; Observed Staining: Cytoplasmic in endothelial cells in blood vessels; Primary Antibody Concentration: 1:100

Applications for GGPS1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GGPS1

GGPS1 is a member of the prenyltransferase family and has geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. The protein is an important precursor of carotenoids and geranylated proteins. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternate Names

6E)-farnesyl diphosphate synthase, dimethylallyltranstransferase, EC 2.5.1.1, EC 2.5.1.10, EC 2.5.1.29, Farnesyl diphosphate synthase, Farnesyltranstransferase, Geranylgeranyl diphosphate synthase, geranylgeranyl diphosphate synthase 1, geranylgeranyl pyrophosphate synthase, Geranyltranstransferase, GGPP synthase, GGPPS, GGPPS1farnesyltranstransferase, GGPPSase

Entrez Gene IDs

9453 (Human)

Gene Symbol

GGPS1

UniProt

O95749 (Human)

Additional GGPS1 Products

Product Documents for GGPS1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GGPS1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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