GLE1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76975

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all GLE1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human Gle1. The immunogen is located within amino acids 540 - 590 of Gle1. Amino Acid Squence: VKDSKVEQQDNFLKR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GLE1 Antibody - BSA Free

Western Blot: GLE1 AntibodyBSA Free [NBP1-76975]

Western Blot: GLE1 AntibodyBSA Free [NBP1-76975]

Western Blot: GLE1 Antibody [NBP1-76975] - Mouse brain tissue lysate with Gle1 antibody at (A) 1 and (B) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: GLE1 Antibody - BSA Free [NBP1-76975]

Immunocytochemistry/ Immunofluorescence: GLE1 Antibody - BSA Free [NBP1-76975]

Immunocytochemistry/Immunofluorescence: GLE1 Antibody [NBP1-76975] - Immunofluorescence of gle1 in mouse brain tissue with gle1 antibody at 5 ug/mL.
Immunohistochemistry-Paraffin: GLE1 Antibody - BSA Free [NBP1-76975]

Immunohistochemistry-Paraffin: GLE1 Antibody - BSA Free [NBP1-76975]

Immunohistochemistry-Paraffin: GLE1 Antibody [NBP1-76975] - Mouse brain tissue with Gle1 antibody at 2.5 ug/ml.
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Applications for GLE1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

5 ug/ml

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GLE1

The proper expression of gene products in eukaryotic cells relies on efficient transport of mRNA molecules out of the nucleus. Gle1 is an essential mRNA export factor in both human and yeast cells. It associates with the nuclear pore complex (NPC) through hCG1 and NUP155 in mammalian cells and in conjunction with inositol hexakisphosphate (IP6), stimulates Dbp5, a member of the DEAD-box helicase family, triggering mRNP remodeling and facilitating RNA export from the nucleus. Recent evidence suggests that mutations in Gle1 causing defects in mRNA export can result in human disease. At least three isoforms of Gle1 are known to exist.

Alternate Names

GLE1 (yeast homolog)-like, RNA export mediator, GLE1 RNA export mediator homolog (yeast), GLE1LGLE1 RNA export mediator-like (yeast), GLE1-like protein, GLE1-like, RNA export mediator, hGLE1GLE1 RNA export mediator (yeast), LCCS, LCCS1, lethal congenital contracture syndrome 1, nucleoporin GLE1

Gene Symbol

GLE1

UniProt

NP_001003722 (Human)

Additional GLE1 Products

Product Documents for GLE1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GLE1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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