Glucagon Antibody (K79bB10)

Novus Biologicals, part of Bio-Techne | Catalog # NB600-1506

Novus Biologicals, part of Bio-Techne
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NB600-1506
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Porcine, Canine, Feline, Guinea Pig, Rabbit

Cited:

Mouse

Applications

Validated:

Dot Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Radioimmunoassay

Cited:

Block/Neutralize, ELISA, IF/IHC, Immunohistochemistry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # K79bB10

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all Glucagon Antibodies »

Product Specifications

Immunogen

Polymerized porcine glucagon.

Reactivity Notes

Not yet tested in other species.

Localization

Secreted

Specificity

The antibody reacts specifically against pancreatic glucagon and exhibits only very weak cross-reaction with gut glucagon (enteroglucagon).Glucagon (K79bB10)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Glucagon Antibody (K79bB10)

Immunohistochemistry: Glucagon Antibody (K79bB10) [NB600-1506]

Immunohistochemistry: Glucagon Antibody (K79bB10) [NB600-1506]

Immunohistochemistry: Glucagon Antibody (K79bB10) [NB600-1506] - Mouse pancreatic islet alpha cells were stained using Monoclonal Anti-Glucagon, clone no. K79bB10, Anti-Mouse IgG-peroxidase and AEC substrate (red). The tissue was counterstained with hematoxylin (blue).

Applications for Glucagon Antibody (K79bB10)

Application
Recommended Usage

Dot Blot

1:100-1:2000

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:2000

Radioimmunoassay

1:100-1:2000
Application Notes
Reacts with pancreatic glucagon. RIA: Use at an assay dependent dilution, affinity constant of 6.1 x 10^8 L/M, reacts with pancreatic glucagon.

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Ascites

Preservative

0.9% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Glucagon

The protein encoded by the Glucagon gene is actually a preproprotein that is cleaved into four distinct mature peptides. One ofthese, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulatingglycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signallingpathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promotenutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an activeenteroglucagon. (provided by RefSeq)

Alternate Names

GCG, GRPP

Entrez Gene IDs

2641 (Human); 14652 (Mouse); 24952 (Rat)

Gene Symbol

GCG

Additional Glucagon Products

Product Documents for Glucagon Antibody (K79bB10)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Glucagon Antibody (K79bB10)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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