GluR7/GRIK3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-20930

Novus Biologicals, part of Bio-Techne
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NBP1-20930
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Key Product Details

Species Reactivity

Validated:

Mouse, Rat

Predicted:

Bovine (100%), Canine (100%), Human (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all GluR7/GRIK3 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-KIRQLPIDSDDSRP corresponding to internal region according to NP_000822.2.

Epitope

C terminus

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for GluR7/GRIK3 Antibody

Western Blot: GluR7/GRIK3 Antibody [NBP1-20930]

Western Blot: GluR7/GRIK3 Antibody [NBP1-20930]

Western Blot: GluR7/GRIK3 Antibody [NBP1-20930] - Analysis in Rat Brain lysate (35ug protein in RIPA buffer) at 0.3ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for GluR7/GRIK3 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:64000

Western Blot

0.3 - 1 ug/ml
Application Notes
WB: Approx. 110 kDa band observed in mouse brain and rat brain lysates (calculated MW of 104 kDa band according to human NP_000822.2, and to rat NP_001106187.1). An additional band of unknown identity was also consistently observed at 39 kDa. This band was successfully blocked by incubation with the immunizing peptide.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: GluR7/GRIK3

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.

Long Name

Glutamate Receptor 7

Alternate Names

EAA5, GLR7, GluK3, GRIK3

Entrez Gene IDs

2899 (Human); 14807 (Mouse); 298521 (Rat)

Gene Symbol

GRIK3

UniProt

NP_000822.2 (Human)

Additional GluR7/GRIK3 Products

Product Documents for GluR7/GRIK3 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for GluR7/GRIK3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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