GluR7/GRIK3 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76387

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all GluR7/GRIK3 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of the human Grik3. The immunogen is located within amino acids 30 - 80 of Grik3. Amino Acid Squence: EYADGPNAQVMNA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GluR7/GRIK3 Antibody - BSA Free

Western Blot: GluR7/GRIK3 AntibodyBSA Free [NBP1-76387]

Western Blot: GluR7/GRIK3 AntibodyBSA Free [NBP1-76387]

Western Blot: GluR7/GRIK3 Antibody [NBP1-76387] - Human brain tissue lysate with Glutamate receptor 7 antibody at (A) 1 and (B) 2 ug/ml.

Applications for GluR7/GRIK3 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GluR7/GRIK3

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik3, also known as glutamate receptor 7, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik3 is highly homologous to the related ionotrophic glutamate receptors Grik2 and Grik1. Grik3 has recently been shown to be an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses as grik3-null mice show significantly reduced short- and long-term synaptic potentiation. Other reports have suggested that different polymorphisms in the Grik3 protein may be associated with neurological defects such as recurrent major depressive disorder and schizophrenia. This Grik3 antibody does not cross-react with Grik2.

Long Name

Glutamate Receptor 7

Alternate Names

EAA5, GLR7, GluK3, GRIK3

Gene Symbol

GRIK3

UniProt

CAI19119 (Human)

Additional GluR7/GRIK3 Products

Product Documents for GluR7/GRIK3 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GluR7/GRIK3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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