Glutamate Receptor 4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-02312

Novus Biologicals, part of Bio-Techne
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NBP1-02312
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all GluR4 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-KKLDQREYPGSETP corresponding to internal region according to NP_001070711.1, NP_001070712.1.

Epitope

internal region

Specificity

This antibody is expected to recognize all reported isforms (NP_000820.3; NP_001070711.1; NP_001070712.1). Reported variants NP_001070712.1 and NP_001106283.1 represent identical protein.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Glutamate Receptor 4 Antibody

Western Blot: Glutamate Receptor 4 Antibody [NBP1-02312]

Western Blot: Glutamate Receptor 4 Antibody [NBP1-02312]

Western Blot: Glutamate Receptor 4 Antibody [NBP1-02312] - Staining of Human Cerebellum lysate (35 ug protein in RIPA buffer). Antibody at 2 ug/mL. Detected by chemiluminescence.
Immunohistochemistry-Paraffin: Glutamate Receptor 4 Antibody [NBP1-02312]

Immunohistochemistry-Paraffin: Glutamate Receptor 4 Antibody [NBP1-02312]

Immunohistochemistry-Paraffin: Glutamate Receptor 4 Antibody [NBP1-02312] - Staining of paraffin embedded Human Cortex. Antibody at 5 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Applications for Glutamate Receptor 4 Antibody

Application
Recommended Usage

Immunohistochemistry

5 - 10 ug/mL

Immunohistochemistry-Paraffin

5 - 10 ug/mL

Peptide ELISA

Detection limit 1:128000

Western Blot

1 - 2 ug/mL
Application Notes
WB: Approx. 90 kDa band observed in human brain (cerebellum) lysates (calculated MW of 99.2 kDa band according to NP_001070711.1). IHC-P: Human cortex shows cytoplasm staining of neuronal cells.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: GluR4

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq]

Long Name

Glutamate Receptor 4

Alternate Names

GluA4, GLURD

Entrez Gene IDs

2893 (Human); 14802 (Mouse); 29629 (Rat)

Gene Symbol

GRIA4

UniProt

NP_000820.3 (Human)

Additional GluR4 Products

Product Documents for Glutamate Receptor 4 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Glutamate Receptor 4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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