Glutathione S-Transferase pi 1/GSTP1 Antibody (003)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-89323

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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Key Product Details

Validated by

Knockout/Knockdown

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 003

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Glutathione S-Transferase pi 1/GSTP1 Antibodies »

Product Summary for Glutathione S-Transferase pi 1/GSTP1 Antibody (003)

Immunogen

This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the N-terminus of the Human Glutathione S-Transferase pi 1/GSTP1.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Glutathione S-Transferase pi 1/GSTP1 Antibody (003)

Western Blot: Glutathione S-Transferase pi 1/GSTP1 Antibody (003) [NBP2-89323]

Western Blot: Glutathione S-Transferase pi 1/GSTP1 Antibody (003) [NBP2-89323]

Western Blot: Glutathione S-Transferase pi 1/GSTP1 Antibody (003) [NBP2-89323] - Lane A: Jurkat Whole Cell Lysate Lane B: K562 Whole Cell LysateLane C: HeLa Whole Cell Lysate Lysates/proteins at 30 ug per lane.Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.Developed using the ECL technique. Performed under reducing conditions.Predicted band size:23 kDa
Glutathione S-Transferase pi 1/GSTP1 Antibody (003) Western Blot: Glutathione S-Transferase pi 1/GSTP1 Antibody (003) [NBP2-89323]

Western Blot: Glutathione S-Transferase pi 1/GSTP1 Antibody (003) [NBP2-89323]

NBP2-89323 used at 1:500 dilution. Lane A: Hela Whole Cell Lysate. Lane B: GSTP1 knockout Hela Whole Cell Lysate. Lysates loaded at 30 ug per lane. Secondary Goat Anti-Rabbit IgG (H+L)[HRP] used at at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 23 kDa.

Applications for Glutathione S-Transferase pi 1/GSTP1 Antibody (003)

Application
Recommended Usage

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Glutathione S-Transferase pi 1/GSTP1

GSTP1 (glutathione-S-transferase, pi 1), also called GST3/DFN7, which is located on chromosome 11q13 , is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (>90%) of prostate carcinomas and is associated with transcriptional down-regulation.

Alternate Names

DFN7, FAEES3, Glutathione STransferase pi 1, GSTP1

Gene Symbol

GSTP1

Additional Glutathione S-Transferase pi 1/GSTP1 Products

Product Documents for Glutathione S-Transferase pi 1/GSTP1 Antibody (003)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Glutathione S-Transferase pi 1/GSTP1 Antibody (003)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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