Glycophorin C Antibody (BRIC4)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-33304

Novus Biologicals, part of Bio-Techne
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NBP2-33304
NBP2-33304-0.025mg
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Haemagglutination, Immunohistochemistry, Immunohistochemistry-Frozen, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # BRIC4

Concentration

0.5 mg/ml

View all Glycophorin C Antibodies »

Product Specifications

Immunogen

Human erythrocytes

Specificity

NBP2-33304 recognises the erythrocyte transmembrane glycoprotein CD236, also known as glycophorin C (GPC). CD236 is an integral membrane protein which carries the Gerbich blood group antigens. Expression of CD236 is not restricted to erythroid cells, but is broadly distributed in both erythroid and non-erythroid tissues. Clone BRIC4 specifically reacts with an epitope located within residues 2-21 of CD236.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Glycophorin C Antibody (BRIC4)

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500

Western Blot

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

TBS

Preservative

0.01% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Glycophorin C

Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, butplays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations havebeen described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duchantigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin Cprotein has very little homology with glycophorins A and B. (provided by RefSeq)

Alternate Names

CD236, CD236 antigen, CD236R, GE, GLPC, glycoconnectin, glycophorin C (Gerbich blood group), glycophorin-C, Glycophorin-D, Glycoprotein beta, GPCMGC126191, GPD, GYPD, MGC117309, MGC126192, PAS-2, PAS-2', Sialoglycoprotein D

Entrez Gene IDs

2995 (Human)

Gene Symbol

GYPC

UniProt

P04921 (Human)

Additional Glycophorin C Products

Product Documents for Glycophorin C Antibody (BRIC4)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Glycophorin C Antibody (BRIC4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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