GMDS Antibody
Novus Biologicals, part of Bio-Techne | Catalog # NBP1-33424
Key Product Details
Validated by
Knockout/Knockdown
Species Reactivity
Validated:
Human
Cited:
Human
Predicted:
Bovine (97%), Mouse (99%), Rat (98%), Rhesus Macaque (99%), Xenopus (93%). Backed by our 100% Guarantee.
Applications
Validated:
Immunohistochemistry, Immunohistochemistry-Paraffin, Knockdown Validated, Western Blot
Cited:
Immunohistochemistry-Paraffin, Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Recombinant protein encompassing a sequence within the center region of human GMDS. The exact sequence is proprietary.
Reactivity Notes
Xenopus laevis (93%), Zebrafish (89%).
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Theoretical MW
42 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Scientific Data Images for GMDS Antibody
Knockdown Validated: GMDS Antibody [NBP1-33424]
Knockdown Validated: GMDS Antibody [NBP1-33424] - a GMDS mRNA level in A549 cells and H1299 cells infected with lentivirus expressing either Scr-shRNA or GMDS-shRNA examined by quantitative real-time PCR (normalized to GAPDH mRNA). Data shown here was one out of three independent experiments (**p < 0.01). b Relative GMDS protein level in A549 cells and H1299 cells infected with lentivirus expressing either Scr-shRNA or GMDS-shRNA examined by western blot. GAPDH protein was used as internal control. c-d. Representative microscope pictures of A549 cells. Image collected and cropped by CiteAb from the following publication (https://bmccancer.biomedcentral.com/articles/10.1186/s12885-018-4524-1) licensed under a CC-BY license.Immunohistochemistry: GMDS Antibody [NBP1-33424]
Immunohistochemistry: GMDS Antibody [NBP1-33424] - Representative images of GMDS IHC staining in human lung adenocarcinoma and adjacent normal tissues. (Magnification, left is 20x, right is 100x). Image collected and cropped by CiteAb from the following publication (https://bmccancer.biomedcentral.com/articles/10.1186/s12885-018-4524-1) licensed under a CC-BY license.Western Blot: GMDS Antibody [NBP1-33424]
Western Blot: GMDS Antibody [NBP1-33424] - GMDS protein level in different cell lines including BEAS-2B (1), MRC-5 (2), HEK-293 (3), A549 (4), H1299 (5), SPC-A-1 (6). A59, H1299 and SPC-A-1 are all human lung adenocarcinoma cell lines. Image collected and cropped by CiteAb from the following publication (https://bmccancer.biomedcentral.com/articles/10.1186/s12885-018-4524-1) licensed under a CC-BY license.Applications for GMDS Antibody
Application
Recommended Usage
Immunohistochemistry
1:100-1:1000
Immunohistochemistry-Paraffin
1:100-1:1000
Western Blot
1:500-1:3000
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Background: GMDS
Alternate Names
EC 4.2.1.47, GDP-D-mannose dehydratase, GDP-mannose 4,6-dehydratase, GMDGDP-mannose 4,6 dehydratase, SDR3E1, short chain dehydrogenase/reductase family 3E, member 1
Entrez Gene IDs
2762 (Human)
Gene Symbol
GMDS
UniProt
Additional GMDS Products
Product Documents for GMDS Antibody
Product Specific Notices for GMDS Antibody
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information go to www.P65Warnings.ca.gov.