GMDS Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-29570

Novus Biologicals, part of Bio-Techne
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NBP3-29570
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Key Product Details

Species Reactivity

Human

Applications

Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all GMDS Antibodies »

Product Specifications

Immunogen

Between 322 and 372

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GMDS Antibody

GMDS Antibody

Immunoprecipitation:GMDS AntibodyNBP3-29570] -

Immunoprecipitation:GMDS AntibodyNBP3-29570] -Detection of human GMDS by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-GMDS antibody NBP3-29570 (lot NBP3-29570-1) used for IP at 6 µg per reaction. GMDS was also immunoprecipitated by rabbit anti-GMDS antibody. For blotting immunoprecipitated GMDS, NBP3-29570 was used at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Applications for GMDS Antibody

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Tris-citrate/phosphate pH 7 -8.

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: GMDS

GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose,the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third stepsof the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX inhumans (MIM 137020).(supplied by OMIM)

Alternate Names

EC 4.2.1.47, GDP-D-mannose dehydratase, GDP-mannose 4,6-dehydratase, GMDGDP-mannose 4,6 dehydratase, SDR3E1, short chain dehydrogenase/reductase family 3E, member 1

Gene Symbol

GMDS

Additional GMDS Products

Product Documents for GMDS Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GMDS Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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