GNG11 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81811

Novus Biologicals, part of Bio-Techne
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NBP1-81811
NBP1-81811-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GNG11 Antibodies »

Product Summary for GNG11 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: EQLRKEVKLQRQQVSKCSEEIKNY

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GNG11 Antibody

Immunohistochemistry-Paraffin: GNG11 Antibody [NBP1-81811]

Immunohistochemistry-Paraffin: GNG11 Antibody [NBP1-81811]

Immunohistochemistry-Paraffin: GNG11 Antibody [NBP1-81811] - Staining of human smooth muscle shows strong cytoplasmic positivity in smooth muscle cells.

Applications for GNG11 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GNG11

GNG11, also known as Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11, is a 73 amino acid that is 8 kDa, plays a role in transmembrane signaling system, its beta and gamma chains are essential for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. This protein has been linked to splenic marginal zone lymphoma disease. The GNG11 protein has shown an interaction with ZHX1, GNB1, SMURF1, AMOTL2, GCG, and over 20 other proteins in several pathways including chemokine signaling pathway, glutamatergic synapse, cholinergic synapse, signal transduction cAMP signaling, G-protein signaling regulation of p38 and JNK signaling mediated by G-proteins, G-protein signaling G-Protein alpha-i signaling cascades, inhibitory action of lipoxins and resolvin E1 on neutrophil functions, signal transduction activation of PKC via G-Protein coupled receptor, molecular mechanisms of cancer, intracellular calcium signaling, CDK5 pathway, JNK pathway, and ERK5 signaling.

Alternate Names

GNGT11G protein gamma-11 subunit, guanine nucleotide binding protein (G protein), gamma 11, guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-11 subunit, guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11

Gene Symbol

GNG11

Additional GNG11 Products

Product Documents for GNG11 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for GNG11 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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