GNPTG Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88443

Novus Biologicals, part of Bio-Techne
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NBP1-88443
NBP1-88443-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GNPTG Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PHALLVYPTLPEALQRQWDQVEQDLADELITPQGHEKLLRTLFEDAGYLKTPEENEPTQLEGGPDSLGFETLENCRKAHKELSKEIKRLKGLLTQHGIPYTRPTETSNLEHLG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GNPTG Antibody

Western Blot: GNPTG Antibody [NBP1-88443]

Western Blot: GNPTG Antibody [NBP1-88443]

Western Blot: GNPTG Antibody [NBP1-88443] - Analysis in control (vector only transfected HEK293T lysate) and GNPTG over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: GNPTG Antibody [NBP1-88443]

Immunohistochemistry-Paraffin: GNPTG Antibody [NBP1-88443]

Immunohistochemistry-Paraffin: GNPTG Antibody [NBP1-88443] - Staining of human stomach shows strong cytoplasmic positivity in glandular cells.

Applications for GNPTG Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GNPTG

GNPTG, also known as N-acetylglucosamine-1-phosphotransferase subunit gamma, is a 305 amino acid that is 34 kDa,; hexamer composed of two alpha, two beta and two gamma subunits, widely expressed; catalyzes the first step in synthesis of a mannose 6-phosphate lysosomal recognition marker, essential for targeting of lysosomal hydrolases to the lysosome. Studies are being performed on the relationship of this protein to mucolipidosis iii gamma, mucolipidosis, mucolipidosis iiic, mucolipidosis ii, dysostosis, short stature, autosomal recessive disease, scoliosis, parkinson's disease, ovarian carcinoma, and retinitis. GNPTG protein involvement has been observed with relation to UPF1 and GNPTAB proteins in the lysosome pathway.

Alternate Names

C16orf27, c316G12.3, CAB56184, GlcNAc-1-phosphotransferase subunit gamma, GNPTAGchromosome 16 open reading frame 27, LP2537, N-acetylglucosamine-1-phosphate transferase, gamma subunit, N-acetylglucosamine-1-phosphotransferase subunit gamma, N-acetylglucosamine-1-phosphotransferase, gamma subunit, RJD9, UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma

Gene Symbol

GNPTG

Additional GNPTG Products

Product Documents for GNPTG Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for GNPTG Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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