GnRHR Antibody (LCHR37)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27924

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # LCHR37

Concentration

0.2 mg/ml

View all GnRHR Antibodies »

Product Summary for GnRHR Antibody (LCHR37)

Immunogen

Recombinant full-length human protein was used as the immunogen for the GnRHR antibody.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Applications for GnRHR Antibody (LCHR37)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1 - 2 ug/ml

Immunohistochemistry-Paraffin

1 - 2 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS, 0.1 mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GnRHR

GnRHR encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.

Long Name

Gonadotropin-releasing Hormone Receptor

Alternate Names

GNRHR1, GRHR, HH7, LHRHR, LRHR, Luliberin

Gene Symbol

GNRHR

UniProt

P30968 (Human)

Additional GnRHR Products

Product Documents for GnRHR Antibody (LCHR37)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for GnRHR Antibody (LCHR37)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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