GR/NR3C1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-78774

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all GR/NR3C1 Antibodies »

Product Summary for GR/NR3C1 Antibody

Immunogen

The immunogen for this product maps to a region between residue 750 and 792 of mouse nuclear receptor subfamily 3 group C member 1 using the numbering given in entry NP_032199 (GeneID 14815).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GR/NR3C1 Antibody

Immunoprecipitation: GR/NR3C1 Antibody [NBP1-78774]

Immunoprecipitation: GR/NR3C1 Antibody [NBP1-78774]

Immunoprecipitation: GR/NR3C1 Antibody [NBP1-78774] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from NIH3T3 cells. Affinity purified rabbit anti-GR antibody used for IP at 6 mcg/mg lysate. GR was also immunoprecipitated by rabbit anti-GR antibody NBP1-78773 which recognizes a disparate epitope.

Applications for GR/NR3C1 Antibody

Application
Recommended Usage

Immunoprecipitation

2-10 mcg/mg lysate
Application Notes
This antibody is not recommended for Western Blot analysis.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: GR/NR3C1

Steroid receptors are ligand-dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Glucocorticoids are a family of steroids necessary for the regulation of energy metabolism and the immune and inflammatory responses. These compounds exert their effect through their interaction with the glucocoticoid receptor (GR) and that complex's subsequent association with DNA. All normal mammalian tissues examined to date have been shown to contain glucocorticoid receptor. The corresponding gene for the glucocorticoid receptor is NR3C1.

Long Name

Glucocorticoid Receptor

Alternate Names

NR3C1

Gene Symbol

NR3C1

UniProt

NP_032199 (Mouse)

Additional GR/NR3C1 Products

Product Documents for GR/NR3C1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for GR/NR3C1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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