Granzyme A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16736

Novus Biologicals, part of Bio-Techne
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NBP2-16736
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Granzyme A Antibodies »

Product Summary for Granzyme A Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human Granzyme A. The exact sequence is proprietary.

Localization

Secreted; Cytoplasmic granule

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

29 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Granzyme A Antibody

Western Blot: Granzyme A Antibody [NBP2-16736]

Western Blot: Granzyme A Antibody [NBP2-16736]

Western Blot: Granzyme A Antibody [NBP2-16736] - Sample (30 ug of whole cell lysate) A: A549 B: Hela C: HCT116 12% SDS PAGE gel, diluted at 1:1000.
Immunohistochemistry-Paraffin: Granzyme A Antibody [NBP2-16736]

Immunohistochemistry-Paraffin: Granzyme A Antibody [NBP2-16736]

Immunohistochemistry-Paraffin: Granzyme A Antibody [NBP2-16736] - Human breast cancer, using Granzyme A antibody at 1:250 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.

Applications for Granzyme A Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Granzyme A

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. [provided by RefSeq]

Alternate Names

CTL Tryptase, CTLA3, Fragmentin-1, GZMA, HF, HFSP

Gene Symbol

GZMA

Additional Granzyme A Products

Product Documents for Granzyme A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Granzyme A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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