GRB10 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16741

Novus Biologicals, part of Bio-Techne
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NBP2-16741
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GRB10 Antibodies »

Product Summary for GRB10 Antibody

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of human GRB10. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

67 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GRB10 Antibody

Western Blot: GRB10 Antibody [NBP2-16741]

Western Blot: GRB10 Antibody [NBP2-16741]

Western Blot: GRB10 Antibody [NBP2-16741] - Sample (30 ug of whole cell lysate) A: HeLa 7. 5% SDS PAGE gel, diluted at 1:1000.
Immunohistochemistry-Paraffin: GRB10 Antibody [NBP2-16741]

Immunohistochemistry-Paraffin: GRB10 Antibody [NBP2-16741]

Immunohistochemistry-Paraffin: GRB10 Antibody [NBP2-16741] - Immunohistochemical analysis of paraffin-embedded U373 xenograft, using antibody at 1:200 dilution.

Applications for GRB10 Antibody

Application
Recommended Usage

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: GRB10

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Alternate Names

Grb-10, GRB10 adapter protein, GRB10 adaptor protein, GRBIR, GRB-IR, growth factor receptor-bound protein 10, Insulin receptor-binding protein Grb-IR, IRBP, KIAA0207, maternally expressed gene 1, MEG1, RSS

Gene Symbol

GRB10

Additional GRB10 Products

Product Documents for GRB10 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for GRB10 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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