Growth Hormone R Antibody (C2)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-41451

Novus Biologicals, part of Bio-Techne
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NBP3-41451
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # C2

Concentration

1 mg/ml

View all Growth Hormone R/GHR Antibodies »

Product Specifications

Immunogen

Immunized with recombinant Human Growth Hormone R (Uniprot#: P10912; Lys315-Thr574 (Uniprot#: P10912)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Applications for Growth Hormone R Antibody (C2)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5-20ug/mL

Immunohistochemistry

5-20ug/mL

Western Blot

0.2-2ug/mL
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS, pH7.4, 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Growth Hormone R/GHR

Growth hormone receptor encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized.

Long Name

Growth Hormone Receptor

Alternate Names

GHR

Gene Symbol

GHR

Additional Growth Hormone R/GHR Products

Product Documents for Growth Hormone R Antibody (C2)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Growth Hormone R Antibody (C2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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